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CBD in the Treatment of PTSD, Alzheimers, Addiction and Mood Disorders
Neuroprotective potential of CBD, based on the combination of its anti-inflammatory and anti-oxidant properties, presently under investigation in numerous neurodegenerative disorder including AD, PD and HD
Previous clinical studies using CBD concentrated on symptom relief in HD rather than on disease progression and did not show any significant improvement
Regarding PD, activation of CB1 receptors (via THC) enhances rather motor disability; however, CBD acts independently of those receptors
major efforts are being directed at finding cannabinoid molecules that provide neuroprotection through their anti-oxidant properties and activate CB2 but not CB1 receptors
Oral CBD in addition to routine psychiatric care was associated with PTSD symptom reduction in adults
CBD also appeared to offer relief from frequent nightmares as a symptom of their PTSD.
CBD seems to blunt the rewarding properties of many drugs (including THC)
Clinical trials currently focus on CBD for people addicted to opioids or cocaine
Animal studies find that CBD reduces the overall level of alcohol intake, anxiety, and impulsivity.
CBD reduces alcohol-related liver and brain damage by its antioxidant, neuroprotective and immunomodulatory properties.
over 1,500 known biochemicals in chocolate that boost mood such as caffeine and theobromine, and compounds that slow anandamide’s breakdown
black pepper (Piper nigrum) contains a compound called guineensine that increases the activity of anandamide
Anandamide is created from arachidonic acid, an essential omega-6 polyunsaturated fatty acid found in meat, eggs, and dairy
CBD oil does not bind to cannabinoid receptors per se, but inhibits the action of the FAAH enzyme, resulting in a net increase in anandamide
Flavonoids also inhibit FAAH
Exercise not only increases anandamide but increases the sensitivity of anandamide receptors
Essential oils: The terpene beta-caryophyllene (βCP) engages CB2 (immune system/anti-inflammatory) Rosemary, Black Pepper, Ylang Ylang, Lavender, Cinnamon and Cloves
Video by Dr. Dawn Elise Snipes on integrative behavioral health approaches including counseling techniques and skills for improving mental health and reducing mental illness.
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