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Video by Dr. Dawn Elise Snipes on integrative behavioral health approaches including counseling techniques and skills for improving mental health and reducing mental illness.
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Post Acute Withdrawal Syndrome (PAWS)
Neurochemical Causes & Interventions
Dr. Dawn-Elise Snipes
Executive Director, AllCEUs Education
~ Learn what PAWS is
~ Explore why PAWS happens
~ Identify steps to take to reduce and cope with PAWS
What is PAWS
~ PAWS affects people who have engaged in addictive behaviors
~ The effects are based on factors
~ Length and amount of use
~ Physical health
~ PAWS begins after acute withdrawal and lasts for up to a year
~ Memories of substance use alter brain functioning (electrical currents and neurotransmitter balance) to promote drug seeking behavior and irritability when blocked from goal achievement
~ Cocaine, Amphetamines, Alcohol
~ Reduce the reuptake of dopamine, increase glutamate and, in high concentrations, to inhibit monoamine oxydase A (MAO-A)
~ Alcohol reduces glutamate’s excitatory effect on NMDA receptors and increases dopamine
~ Co-Administration of nicotine and alcohol increases alcohol’s rewarding effects
~ Nicotine stimulates the dopamine and the reward center and is responsible for the mood elevation and apparent improvement in cognitive function.
~ Chronic stimulation by nicotine the GABAergic neurons are desensitized and thus lose their inhibitory effect on dopamine which reinforces the addiction by inducing craving
~ Opioids: Opioid, Serotonin, Dopamine
~ Benzodiazepines: GABA, Serotonin
~ In chronic substance abuse, the brain comes to rely on the drug to maintain the high degree of pleasure associated with the artificially elevated levels of some neurotransmitters in its reward circuits.
~ The brain can even adapt to these high neurotransmitter levels by making new receptors which produces depression or anxiety and cravings if consumption ceases and neurotransmitter levels return to normal.
~ In a factory think of dopamine like one of the raw materials needed to make a product (happiness)
~ Normally dopamine is on autoshipment—a steady, regular supply to so the factory can produce a steady supply of “happiness”
~ The manager sees a “deal” on dopamine and wants to increase his departments revenue really quickly and get a promotion. He triples the autoshipment.
~ Emotional outbursts or lack of emotion
~ Anxiety and irritability
~ Depression and anhedonia
~ Difficulty dealing with stress
~ Having a hard time sleeping, strange dreams, and changes in sleep patterns
~ Memory problems that make it hard to learn new things
~ Trouble thinking clearly, making decisions, and solving problems
~ Dizziness, problems with balance and delayed reflexes
Neurotransmitters and Receptors
~ Endogenous opioids reduce the amount of GABA released
~ Reduced GABA increases dopamine
~ Dopamine is the perseveratory neurochemical
~ Norepinephrine is responsible for attention, and alertness
~ Glutamate is the main excitatory neurotransmitter.
~ Serotonin has both stimulatory and calming influences
~ Cannabinoid receptors are involved in regulating mood, memory, appetite, pain, cognition, and emotions.
Interventions (MR ESCAPER)
~ Goal: To regulate the temperature of the “bath”
~ Meditation / Breathing
~ Relationships (with sober social supports)
~ Circadian rhythm restabilization
~ Pleasurable activities
~ Eat healthfully
~ Recovery involves creating a new life where it is easier to not use
~ Be completely honest with yourself and others
~ Ask for help
~ Practice self-care. Make a daily routine that allows time to rest and relax.
~ Create and maintain your recovery boundaries
~ Identify and stay in touch with your support system. It can be family, friends, counselors, health care providers, spiritual or religious group.
~ Be compassionate and treat yourself with patience and understanding, giving yourself time to heal